What gallstones are and why they form
The gallbladder is a small, pear-shaped organ that sits beneath the liver. It stores the bile the liver produces and squeezes it into the small intestine when a meal, particularly a fatty one, arrives. When the balance between cholesterol, bile salts and bilirubin in bile is disturbed, stones can form inside the gallbladder — sometimes as fine as grit, sometimes several centimetres across. Older age, female sex, pregnancies, excess weight, rapid weight loss and a family history of gallstones are all recognised risk factors.
Many stones never cause a single symptom and turn up incidentally on an ultrasound ordered for another reason. When they do cause trouble, the classic pattern is biliary colic: pain in the upper right abdomen or just below the breastbone, often beginning after a fatty meal, sometimes radiating to the back or right shoulder, and frequently accompanied by nausea. Bloating, indigestion and intolerance of fatty food are also commonly reported. Because reflux, gastritis and bowel conditions can produce similar complaints, part of the assessment is confirming that the symptoms really come from the gallbladder.
- Recurrent upper right abdominal pain, often after fatty meals
- Abdominal pain with fever that does not settle within a few hours
- Yellowing of the eyes or skin, dark urine, pale stools
- Persistent nausea, vomiting or loss of appetite
Do all gallstones need surgery?
No. The decision rests on what the stones are doing, not simply on their presence. Silent stones found by chance on a scan can often be watched rather than operated on. In that case the patient is told which symptoms should prompt a return visit, and follow-up is arranged where appropriate.
Once stones start causing symptoms the picture usually changes, because episodes of pain tend to recur and can eventually lead to inflammation. Repeated attacks of biliary colic, inflammation of the gallbladder (cholecystitis), jaundice caused by a stone slipping into the main bile duct, and gallstone-related pancreatitis are the situations in which surgery is normally discussed. A few specific findings may lead to surgery being recommended even without symptoms.
At İzmir Cerrahi Merkezi this assessment is made individually for each patient, weighing age, other medical conditions, how often symptoms occur and what the imaging shows. Any decision about surgery can only be reached after examination, blood tests and appropriate imaging, and it is made together with the patient.
- Repeated episodes of biliary colic
- Current or previous gallbladder inflammation (cholecystitis)
- Stones that have passed into the bile duct, with jaundice
- A previous episode of gallstone pancreatitis
- A calcified (porcelain) gallbladder or polyps with certain features
Diagnosis and preparation for surgery
Abdominal ultrasound is the first and most useful test: it shows the stones, the thickness of the gallbladder wall and the width of the bile ducts. Blood tests, including liver function tests and, when relevant, pancreatic enzymes, complete the picture. If a stone in the main bile duct is suspected, an MRCP scan or endoscopic ultrasound may be requested; a duct stone often has to be cleared endoscopically before the gallbladder itself is removed.
Once surgery is planned, an anaesthetic assessment follows. Heart, lung and metabolic conditions, regular medication and above all blood-thinning drugs are reviewed in advance, and your surgeon will advise whether any of them should be paused. You will be asked to fast for a set period before the operation, and stopping smoking beforehand helps recovery. Patients travelling from abroad should send their records and existing scans ahead, so the plan can be reviewed before the journey.
How laparoscopic cholecystectomy is performed
The operation is carried out under general anaesthesia. The abdomen is gently inflated with carbon dioxide to create working space, and a camera and fine instruments are introduced through three or four small incisions. The gallbladder is carefully separated from the duct and artery that supply it; these are secured with clips, and the gallbladder is then removed through one of the incisions. The aim is not to remove the stones alone but the organ that keeps producing them, which is why the standard operation is removal of the whole gallbladder.
The bile ducts can be imaged during the operation if the situation calls for it. Where inflammation is advanced, adhesions are dense, or the anatomy cannot be identified with confidence, the surgical team may decide to convert to open surgery. This is not a failure but a judgement that puts safety first, and the possibility is discussed beforehand. The procedure typically takes around an hour, though this varies with the degree of inflammation and the individual anatomy.
Like any operation, it carries risks — bleeding, wound problems and injury to the bile duct among them. These are explained in detail during the pre-operative consultation and weighed against the risks of leaving symptomatic stones untreated.
Recovery and getting back to normal
After an uncomplicated keyhole operation most patients are up and taking fluids the same day, and discharge is usually the same evening or the following day. How long you stay depends on the degree of inflammation, other medical conditions and your general recovery, so it varies from patient to patient.
Some discomfort at the incision sites is normal in the first few days, as is shoulder-tip pain caused by the gas used during surgery; both usually settle quickly and respond to simple painkillers. Walking is encouraged early. Desk-based work is typically possible within about a week, while heavy lifting and strenuous exercise are usually deferred for a few weeks. These are average expectations rather than fixed rules.
Contact the team promptly if you develop a fever, pain that steadily worsens rather than eases, persistent vomiting, yellowing of the eyes, or discharge from a wound. Patients travelling home by air should agree the timing with their surgeon before booking a return flight.
Living without a gallbladder
This is the question almost everyone asks: will digestion suffer once the gallbladder is gone? Bile is made by the liver, not the gallbladder — the gallbladder is only a reservoir. After removal the liver carries on producing bile, which now flows steadily and directly into the intestine instead of being stored between meals. Most people return to a normal diet and need no lasting restrictions.
In the first few weeks it helps to avoid very fatty or fried food and large portions, and to eat smaller meals more often. Some people notice wind, bloating or looser stools after fatty meals; this usually eases with time. If symptoms persist, dietary adjustment or medication can be discussed with your surgeon.
When pain does not fully resolve after surgery, the sensible next step is to reassess whether the original symptoms were truly biliary or whether reflux, gastritis or a bowel condition is contributing. At İzmir Cerrahi Merkezi that assessment is given the same attention before and after an operation. If you have recurring upper right abdominal pain, stones seen on an ultrasound, or a previous episode of gallbladder inflammation, our surgeons can examine you and talk through the options that fit your situation.
Frequently asked questions
Can gallstones be dissolved with medication?
Dissolution therapy is only considered for a small, carefully selected group of stones. It works slowly, must be taken for a long time, and stones commonly return once treatment stops. For stones that are causing symptoms, surgery remains the accepted treatment. What suits you can only be judged after examination and imaging.
I have no symptoms — should my stones still be removed?
Silent stones can usually be monitored rather than operated on. Surgery may still be advised in specific circumstances, such as a calcified gallbladder wall, polyps with certain features, or a history of previous attacks. It is an individual decision that requires assessment.
Can the stones be removed and the gallbladder left in place?
The gallbladder itself is the source of the problem, so removing only the stones tends to be followed by new ones. Standard treatment is removal of the entire gallbladder.
Will I need a special diet for the rest of my life?
No. Avoiding fatty and fried food and keeping meals small helps in the first few weeks, after which most people eat normally. Some notice looser stools or bloating after rich meals for a while; this generally settles.
Can keyhole surgery turn into open surgery?
Yes. If inflammation is severe, adhesions are dense, or the anatomy cannot be safely identified, the surgeon may convert to an open operation. This is a safety decision rather than a complication, and it is discussed with you beforehand.
I am travelling to İzmir for treatment — how long should I plan to stay?
Plans should be made individually, since the length of stay depends on the operation itself, your recovery and any pre-operative tests still needed. Send your existing scans and reports in advance so the team can advise on realistic timing before you book travel.